SHGB Test

£45.00

The SHBG (Sex Hormone-Binding Globulin) Blood Test measures the levels of SHBG in the bloodstream. This test is often used to help diagnose and monitor various conditions, including hirsutism (excessive hair growth), hypogonadism (low testosterone levels), and polycystic ovary syndrome (PCOS). It provides valuable insights into hormone balance and potential underlying health issues.

SHGB (Sex Hormone Binding Globulin) Blood Test

Free next-day delivery

Results within 2 days

1 biomarker(s)

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Biomarkers

SHGB (Sex Hormone Binding Globulin)

Sex Hormone-Binding Globulin (SHBG) is a protein that binds to sex hormones, such as testosterone and oestrogen, in the bloodstream.

High SHBG Levels: These may occur in conditions associated with increased oestrogen levels, including pregnancy, liver diseases like cirrhosis, and certain types of hormone-producing tumors.
Low SHBG Levels: These are often seen in conditions associated with reduced oestrogen levels, such as menopause, androgen excess, and obesity.
The SHBG test is primarily used to diagnose conditions linked to abnormal testosterone or oestrogen levels. Additionally, it can be used to monitor the effectiveness of treatments targeting these hormonal imbalances.

Information

Symptoms of Low SHGB

Low levels of Sex Hormone-Binding Globulin (SHBG) may lead to a range of symptoms, including:

Weight gain
Depression
Irritability
Muscle weakness
Bone loss
Hot flashes
Fatigue
These symptoms often result from hormonal imbalances and may vary in severity depending on the underlying condition.

Additional Information

Sex Hormone-Binding Globulin (SHBG) is a protein produced by the liver that binds to three key sex hormones: testosterone, dihydrotestosterone (DHT), and oestradiol. By binding to these hormones, SHBG transports them through the bloodstream to their target tissues.

Factors Affecting SHBG Levels
SHBG levels can be influenced by several factors, including:

Age and gender
Liver health
Obesity
Medications
Impact on Hormone Activity
High SHBG levels: Reduce the amount of active hormone available to bind to receptors, potentially leading to symptoms of hormone deficiency.
Low SHBG levels: Increase the amount of active hormone available, potentially causing symptoms of hormone excess.
Medications and SHBG
Certain medications can affect SHBG levels, including:

Androgen Deprivation Therapy (ADT): Used in prostate cancer treatment.
Oestrogen Replacement Therapy
Some oral contraceptives
It is important to inform your doctor about any medications you are taking before undergoing an SHBG test, as these may influence the results.

The SHBG Blood Test
The SHBG blood test is a simple, safe, and reliable way to measure SHBG levels in your blood. It is often used to help diagnose and manage conditions such as:

Hirsutism (excessive hair growth)
Hypogonadism (low testosterone levels)
Polycystic Ovary Syndrome (PCOS)
If you are taking medications that may affect SHBG levels, discussing this with your doctor before testing ensures accurate results.

Symptoms of High SHGB

Elevated levels of Sex Hormone-Binding Globulin (SHBG) can lead to various symptoms, including:

Breast enlargement (gynecomastia)
Decreased sex drive
Infertility
Cushing’s disease
Obesity
Polycystic ovary syndrome (PCOS)
Acromegaly
These symptoms often stem from hormonal imbalances and may indicate underlying health conditions requiring further evaluation.

Why take a test?

The SHBG blood test is a safe, reliable, and effective method for measuring Sex Hormone-Binding Globulin levels in your blood. It provides valuable information that can aid in diagnosing various conditions, including hirsutism (excessive hair growth), hypogonadism (low testosterone levels), and polycystic ovary syndrome (PCOS).

%

of Hirsutism cases are cause by Polycystic ovary syndrome

According to the National Institute for Health and Care Excellence (NICE), a significant number of hirsutism cases—characterized by the excessive growth of coarse terminal hair in specific areas of the body in women—are caused by polycystic ovary syndrome (PCOS).

%

of women in the UK are thought to have polycystic ovary syndrome (PCOS)

According to the NHS, a significant proportion of women in the UK are believed to have polycystic ovary syndrome (PCOS), although many may not experience noticeable symptoms. PCOS can also increase the risk of developing other health issues later in life.

Experts Opinion on SHGB Blood Tests

SHBG is a protein that binds to most sex hormones, such as testosterone and oestrogen. When these hormones are bound to SHBG, they become inactive and unavailable for the body to use. Measuring SHBG levels in the blood helps assess whether hormone levels are balanced and functioning at optimal levels.

Dr Sameer Nakedar

MBBS, MRCGP, PGCert

How to take a SHGB Test

Collecting a blood sample for a finger-prick home test is simple and easy. For detailed instructions on how to perform the test at home, watch the video below.

How to take a SHGB Test

1. Pick your home test

We offer a wide range of tests to meet your health needs. Order today for next-day delivery within the United Kingdom and skip the wait at a doctor’s office or clinic. Use our quiz to easily find the perfect test for you.

2. Take your test

Activate your test and collect your sample in the morning using the simple finger-prick method, which takes about 5 minutes. Afterward, return your sample the same day using the prepaid shipping label provided.

3. Results within 48 hours

Receive verified results along with detailed insights into what your biomarkers mean. Order now and take the first step toward a healthier you!

SHGB Test Information

Specification of SHGB Test

Test Name: SHBG Test
Also Known As & Related Tests: Sex Hormone-Binding Globulin Blood Test, Testosterone-Estrogen Binding Globulin Test, Androgen-Binding Protein Test
Biomarkers Tested: SHBG (Sex Hormone-Binding Globulin)
Test Tube: SST (Gold Microtainer)
Brand: Welzo
Turnaround Time: Approximately 24 hours
Lab Test Ranges:
Test Kit Marking: MHRA/UKCA
Lab Location: United Kingdom

What does a SHGB Test for?

An SHBG test measures the levels of Sex Hormone-Binding Globulin (SHBG) in the blood. SHBG is a protein that binds to sex hormones like testosterone and oestrogen, helping to regulate their availability in the body.

Are SHGB Tests available on the NHS?

SHBG tests are available through the NHS, subject to eligibility criteria, medical consultations, and local guidelines.

FAQs

What conditions are associated with high or low SHGB?

Several conditions are associated with high or low SHBG levels. High SHBG levels have been linked to conditions such as polycystic ovary syndrome (PCOS) and thyroid disorders. On the other hand, low SHBG levels are commonly associated with conditions like obesity and type 2 diabetes. If you experience symptoms that may be related to abnormal SHBG levels, it’s important to consult with a doctor for further evaluation and appropriate management.

What are the symptoms of high SHGB?

There are no specific symptoms directly caused by high SHBG levels. However, elevated SHBG levels may indicate an underlying medical condition. For example, high SHBG has been linked to conditions like polycystic ovary syndrome (PCOS) and thyroid disorders. If you experience symptoms that may be related to abnormal SHBG levels, it is important to consult a doctor for further evaluation and proper diagnosis.

Where do I send my sample?

You will receive a prepaid return label to send your health test samples back to our lab for analysis. Additionally, we will provide clear instructions and return information via email to guide you through the process.

What do I need to do before my test? i.e. fast, no drinking, etc

If fasting or limiting alcohol intake is required before your blood test, we will send personalized instructions to you via email after your order is placed. However, most tests can be completed without the need for fasting.

When will I get my results/how will I receive my results?

Results are typically processed within 2–3 working days. If a sample is sent over the weekend (which we do not recommend), you will receive your results within 2–3 days from Monday. Once your results and personalized report are ready, you will receive an email notification prompting you to log in to the Welzo online platform to view them.

What are low or high levels of SHGB?

There is no single “normal” SHBG level, as it can vary depending on factors like age, sex, and individual health. However, in general:

Low SHBG levels are typically considered below 10 nmol/L in women and below 20 nmol/L in men.
High SHBG levels are generally considered above 30 nmol/L in women and above 40 nmol/L in men.
If your SHBG levels fall outside these ranges, it could indicate an underlying medical condition, and it is important to consult a doctor for further evaluation.

Is it better to have high or low levels of SHGB?

The ideal SHBG level depends on the individual’s health and specific circumstances. For example, low SHBG levels may increase the risk of conditions like osteoporosis, although more research is needed to fully understand this connection. On the other hand, high SHBG levels have been linked to an elevated risk of heart disease. Ultimately, the impact of SHBG levels varies from person to person, so it’s important to discuss your individual situation with a healthcare provider to determine what’s best for you.

What if my results show that I’m outside the normal range?

If your results fall outside the normal range and raise concerns, it is important to contact your GP or emergency services immediately by calling 111 or 999. Please note: If you feel unwell, experience symptoms, or are concerned about your health, do not wait for your results to be issued—seek medical attention right away.

Disclaimer: If your test results are abnormal, we are not responsible for follow-up treatments or notifying a healthcare professional. By taking the test, you agree to take the necessary steps to follow up with a healthcare provider independently.

Where does my information go, and is the system secure?

When you register with our platform, your personal information is automatically encrypted and pseudonymized to ensure privacy. Your sample will be sent to our lab and processed using an encrypted HL7 file, a globally recognized standard for exchanging electronic health records (EHRs). To further protect your data, your information is pseudonymized with a unique, unidentifiable alphanumeric code, enhancing both security and anonymity.

You can also request the deletion of your data at any time by emailing us at hello@welzo.com. Your privacy and security are our top priorities.

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